Workshop Details
Proton Transfer in Biology
07/30/2007 - 08/03/2007
Meeting Description:

Proton transfer reactions are of central importance in all areas of study concerning redox systems, ionic reactions and chemical catalysis, and there is significant recognition of the connection between biological and chemical reactions involving carbon acids and other very weakly acidic functionalities, i.e., the classical area of acid-base catalysis. However, the lack of detailed structural information has greatly impeded meaningful attention being paid to mechanisms of long-distance proton transport, in spite of its central role in bioenergy conversion by chemiosmotic systems. Recent successes in structure determination of the major energy-transducing membrane proteins have now set the stage for real advancement is this area. Just as the photosynthetic reaction center was invaluable for the development and testing of theoretical understanding of electron transfer in aperiodic systems, generally, so can proton transporting proteins can inform such developing fields as polymer membrane designs for fuel cells, non-aqueous electrolyte solutions, and matrix materials for heterogeneous catalysis. This is becoming an important focus area of productive cross-disciplinary exchange. The objective of the conference is to bring together scientists in diverse fields, who share interests in the structure and function of systems that transport protons and water. The emphasis is on long-range movements in biological membranes and model systems, but short-range proton and hydrogen atom transfers are also included to provide understanding of the nature of rate limiting events. The contributing fields include membrane biophysics, electrophysiology, structural biology of membrane proteins, bioenergetics, theoretical approaches to proton transfer, coupling of proton movements to electron transfer and conformational changes, molecular dynamics simulations, computation of protein electrostatics, spectroscopy and sensory transduction.

Meeting Venue:

Telluride Intermediate School
725 W Colorado Ave Telluride CO 81435

Registered Meeting Participants:
Participant Organization Arrival Information Departure Information Interested in Sharing Transportation?
Adelroth, Pia Stockholm University
Agmon, Noam Hebrew Univ.
Balashov, Sergei UCI (U.CA, Irvine)
Brzezinski, Peter Stockholm University
Crofts, Antony UIUC
Cui, Qiang Univ. of Wisc. Madison
Cukierman, Samuel Loyola Medical Center/Physiology
DeCoursey, Thomas Rush University
Garcia-Moreno, Bertrand Biophysics/Johns Hopkins
Gennis, Robert University of Illinois
Grosman, Claudio University of Illinois at Urbana-Champaign
Gunner, Marilyn CCNY Physics Dept
Gutman, Menachem Tel Aviv University
Haines, Thomas Rockefeller University
Hummer, Gerhard National Institutes of Health
Hunte, Carola Max-Planck-Institute for Biophysics
Isom, Daniel Hellinga Lab, Duke University
Kaila, Ville University of Helsinki
Lancaster, Roy Max Planck Institute of Biophysics
Mulkidjanian, Armen School of Physics, University of Osnabrueck
Nachliel, Esther Tel Aviv University
Paddock, Mark University California, San Diego
Parul, Dzmitry LANL
Swanson, Jessica NIH NRSA Fellow
Voth, Gregory A. University of Utah
White, Stephen Univ. of California, Irvine
Wraight, Colin University of Illinois

Telluride Science Research Center
Post Office Box 2429, Telluride CO 81435
Tel: + 970.708.4426
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