Workshop Details
Challenges in Dissecting and Understanding Nucleic Acid Electrostatics
06/26/2017 - 06/30/2017
Meeting Description:

This workshop aims to address major challenges in nucleic acid electrostatics and their folding and functional processes. DNA and RNA - biological macromolecules with central roles in information storage, gene expression and function - are polyelectrolytes. Thus, an understanding of their structural and functional properties requires a conceptual and quantitative accounting of their electrostatic properties.

However, the polyanionic character of nucleic acids results in complex electrostatic interactions with counter ions, including inner and outer sphere metal ions and formation of an ion cloud surrounding DNA and RNA. These complexities are currently poorly understood and are difficult to model. Further, their understanding will require advances in both theory and experiment and, critically, an interplay between them.

This meeting will bring together experimentalists and theorists to explore avenues for working collaboratively in a more focused manner - to share perspectives about the state-of-the-art RNA electrostatics (theory and experiment) and to identify experimental approaches that would be most helpful in testing and addressing key bottlenecks in theory and modeling. A key goal will be to work toward the development of a framework that will allow blind computational predictions to be independently tested via experiment to meet a critical need of this community.

Notes:

The registration fee includes five breakfasts, one lunch, a Wednesday-night BBQ picnic, and all the coffee and snacks you can eat.

If you are interested in attending a meeting, but have not received an invitation, please contact the workshop organizer about availability before registering. Most TSRC meetings are very small, typically only about 25 people. If you have registered for a meeting you were not invited to, you may be subject to a $100 fee.

Meeting Venue:

Telluride Intermediate School
725 W Colorado Ave Telluride CO 81435

Registered Meeting Participants:
Participant Organization Arrival Information Departure Information Interested in Sharing Transportation?
Al-Hashimi, Hashim Duke University 6/26
6/30
Bergonzo, Christina NIST 6/25
6/29
Y
Case, David Rutgers University 6/25
6/30
Y
Chen, Shi-Jie University of Missouri-Columbia 6/25
6/29
Feig, Michael Michigan State University 6/25
7/1
Galindo, Rodrigo University of Utah 6/25
6/30
Gebala, Magdalena Stanford University 6/25
7/1
Y
Grishaev, Alexander National Institute of Science and Technology
Havenith, Martina Ruhr University Bochum 6/25
7/1
Y
Herschlag, Dan Stanford University
Lemkul, Justin University of Maryland, Baltimore 6/25
6/30
Lilley, David University of Dundee 6/24
6/29
Maddocks, John H. EPFL FSB MATH LCVMM 6/25
6/30
Merriman, Dawn Duke University 6/25
6/30
PAN, FENG NC State University 6/24
6/30
Pettitt, Monte University of Texas Medical Branch 6/25
6/30
Pollack, Lois Cornell University 6/25
6/30
Ranganathan, Srivathsan University at Albany 6/25
6/30
Y
Saleh, Omar UC Santa Barbara 6/25
7/1
Stelling, Allison L. Duke University
Thomas, Dennis Pacific Northwest National Laboratory 6/25
6/29
Yoo, Jejoong UIUC 6/25
6/30
Zettl, Thomas Ludwig Maximilian University of Munich 6/25
7/1
Y

Telluride Science Research Center
Post Office Box 2429, Telluride CO 81435
Tel: + 970.708.4426
Email: info@telluridescience.org
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