Workshop Details
Cystic Fibrosis: Ecology, Evolution, and Eradication
08/01/2011 - 08/05/2011
Meeting Description:

New approaches to cystic fibrosis (CF) have recently become available in both the experimental and the theoretical arenas. In the experimental arena, large scale metagenomics on sputum samples has revealed many more species present than traditional culturing methods. MRI scans of CF promise location specific growth data observable often and giving some of the same information that only CT scans could provide. These techniques have made the dynamics of the CF lung as an ecosystem accessible to observation. Such observation needs guidance from theory. The workshop will explore ecological and evolutionary approaches to modeling the CF lung and their application to devising an optimal treatment regimen. The 2009 TSRC workshop on this theme focused on building mathematical models. Much of that work that has been done, and will be summarized in the first couple of days of the meeting. But as with all good Telluride workshops, the aim is to do research on-site. One-hour talks last two hours due to intensive probing from the audience. Come prepared to give chalk talks and/or Powerpoint about your work...especially things that you think are important.

Notes:

GOAL: IDENTIFY WEAKNESSES IN THE CYSTIC FIBROSIS ECOSYSTEM THAT CAN BE THERAPUTICALLY EXPLOITED...


Possible Products

A) Models of CF lung that help us identify evolutionary and ecological instabilities

B) Identify missing datasets that are critical for managing CF as an ecosystem

C) Exchange information amongst biologists, doctors, and mathematicians


Possible talks/discussion sessions

Paul Rainey - Evolutionary instabilities and the CF lung

Forest Rohwer - Microbial ecology and relationship to CF lung

Peter Salamon - Physiological models and optimal disease treatments

Doug Conrad - Clinicians view of treating CF

Dana Willner - Viral communities in the CF lung


Meeting Venue:

Telluride Intermediate School
725 West Colorado Ave Telluride C0 81435

Cystic Fibrosis: Ecology, Evolution, and Eradication Registered Meeting Participants:
Participant Organization
Barr, Jeremy SDSU Research Foundation
Conrad, Douglas UC San Diego
Dutilh, Bas E SDSU
Edwards, Robert San Diego State University
Evangelista, Jose UCSD
Felts, Ben SDSU
Hand, Carol SDSU
Harris, Kirk University of Colorado
Haynes, Matthew San Diego State University
Jelsbak, Lars Technical University of Denmark
Khasin, Michael MIT
Kong, Weidong UCSF
Lim, Yan Wei San Diego State University
LiPuma, John University of Michigan
Rainey, Paul Massey University
Rohwer, Forest SDSU Research Foundation
Salamon, Peter San Diego State University
Schmieder, Robert San Diego State University
Shaw, Kevin UC San Diego
Singh, Pradeep University of washington
Theilmann, Rebecca UCSD
Wagner, Brandie University of Colorado Denver

Telluride Science Research Center
Post Office Box 2429, Telluride CO 81435
Tel: + 970.708.4426
Email: info@telluridescience.org
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